Downstream Process Scientist

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What you need to know

I am looking for a Downstream Process Scientist who will assist with the development and validation of processes for recombinant antibodies for veterinary use for Downstream Processing. This is a permanent job and is located in Tullamore.

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This is a cross functional role in that it will also support upstream production and development for the manufacturing of products. As well as providing hands-on support for all manufacturing activities including purification processes, integrity testing, buffer/media preparation and cell culture, you will be using purification techniques such as chromatography, ultrafiltration/ diafiltration and virus filtration.

Key duties & responsibilities:

  • Support the development, optimisation, scale-up, validation and commercial manufacture of a monoclonal antibody production processes.
  • Strict adherence to GMP, working in a cleanroom environment and executing batch records.
  • Support the writing and updating of Batch Manufacturing Records, SOPs, and other quality documents required for GMP manufacture.
  • Participate in Quality and Safety regulatory audits and completion of deviations and investigations into non-conformances.
  • Work with external partners to provide the necessary technical support for successful completion of projects including the transfer of processes into the facility.
  • Identify continuous improvement initiatives and action plans to implement operational excellence and lean practices.

What are we looking for?

  • BSc, MSc or PhD in Chemical/Biochemical Engineering or related Biological Sciences
  • Industry experience of working in bioprocess development and/or purification processing
  • Knowledge of analytical methods required for protein characterisation.
  • Knowledge of key suppliers of process materials and equipment including disposable systems.
  • Excellent project management capability
  • Knowledge and understanding of the workings of protein purification techniques using Unicorn software or similar automated control system would be a distinct advantage

Apply for this job now or get in touch with Gareth on 090 6490485.

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Recruitment Consultant: Gareth Morris

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